Steven R Smith Selected Research

lorcaserin

1/2019	Lorcaserin and Renal Outcomes in Obese and Overweight Patients in the CAMELLIA-TIMI 61 Trial.
11/2018	Effect of lorcaserin on prevention and remission of type 2 diabetes in overweight and obese patients (CAMELLIA-TIMI 61): a randomised, placebo-controlled trial.
1/2018	Design and rationale for the Cardiovascular and Metabolic Effects of Lorcaserin in Overweight and Obese Patients-Thrombolysis in Myocardial Infarction 61 (CAMELLIA-TIMI 61) trial.
1/2018	Cardiovascular Safety of Lorcaserin in Overweight or Obese Patients.
1/2017	Coadministration of lorcaserin and phentermine for weight management: A 12-week, randomized, pilot safety study.
10/2014	Early weight loss while on lorcaserin, diet and exercise as a predictor of week 52 weight-loss outcomes.
7/2013	Echocardiographic assessment of cardiac valvular regurgitation with lorcaserin from analysis of 3 phase 3 clinical trials.
7/2012	Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM study.
10/2011	A one-year randomized trial of lorcaserin for weight loss in obese and overweight adults: the BLOSSOM trial.
3/2011	Lorcaserin, a 5-HT(2C) receptor agonist, reduces body weight by decreasing energy intake without influencing energy expenditure.

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Steven R Smith Research Topics

Disease

48	Insulin Resistance 11/2019 - 06/2002
45	Weight Loss (Weight Reduction) 01/2022 - 07/2004
39	Obesity 09/2021 - 09/2002
32	Overweight 01/2022 - 11/2002
24	Type 2 Diabetes Mellitus (MODY) 11/2019 - 12/2003
24	Body Weight (Weight, Body) 06/2019 - 11/2002
14	Inflammation (Inflammations) 06/2020 - 09/2002
9	Weight Gain 12/2020 - 01/2005
5	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2020 - 10/2004
5	Cardiovascular Diseases (Cardiovascular Disease) 01/2018 - 11/2002
4	Abdominal Obesity 01/2022 - 11/2007
3	Myocardial Infarction 01/2019 - 03/2016
3	Heart Failure 01/2018 - 12/2004
3	Hyperinsulinism (Hyperinsulinemia) 08/2016 - 03/2010
3	Nausea 10/2011 - 09/2009
3	Hypoxia (Hypoxemia) 08/2010 - 02/2006
3	Bone Resorption 12/2008 - 04/2003
2	Hyperphagia (Overeating) 12/2020 - 01/2012
2	Metabolic Diseases (Metabolic Disease) 01/2020 - 01/2018
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2018 - 01/2018
2	Hypoglycemia (Reactive Hypoglycemia) 01/2018 - 07/2012
2	Stroke (Strokes) 01/2018 - 03/2016
2	Diabetes Mellitus 07/2012 - 09/2010
2	Dizziness (Lightheadedness) 10/2011 - 07/2010
2	Headache (Headaches) 10/2011 - 07/2010
2	Hypoadiponectinemia 02/2008 - 11/2007
2	Atherosclerosis 07/2006 - 01/2006
2	Sleep Deprivation 08/2003 - 08/2003

Drug/Important Bio-Agent (IBA)

30	LipidsIBA 01/2022 - 06/2002
25	Insulin (Novolin)FDA Link 01/2019 - 11/2002
21	Glucose (Dextrose)FDA LinkGeneric 06/2020 - 11/2002
13	Proteins (Proteins, Gene)FDA Link 01/2021 - 02/2009
12	lorcaserinIBA 01/2019 - 03/2009
11	CarbohydratesIBA 01/2022 - 07/2005
8	Nonesterified Fatty Acids (NEFA)IBA 12/2020 - 01/2005
8	Triglycerides (Triacylglycerol)IBA 06/2011 - 01/2005
7	Pioglitazone (Actos)FDA Link 04/2017 - 07/2004
7	Messenger RNA (mRNA)IBA 01/2016 - 12/2003
7	AdiponectinIBA 01/2013 - 06/2006
6	5-HT2C Serotonin ReceptorIBA 01/2019 - 07/2010
6	Fatty Acids (Saturated Fatty Acids)IBA 05/2007 - 08/2002
4	Dietary Fats (Dietary Fat)IBA 12/2020 - 09/2002
4	LeptinIBA 10/2013 - 11/2007
4	C-Reactive ProteinIBA 04/2013 - 06/2006
4	Caffeine (No Doz)FDA LinkGeneric 05/2007 - 08/2003
3	Biomarkers (Surrogate Marker)IBA 06/2021 - 04/2006
3	HDL LipoproteinsIBA 12/2020 - 01/2006
3	HDL CholesterolIBA 12/2020 - 06/2008
3	CreatinineIBA 01/2019 - 04/2003
3	Phentermine (Adipex-P)FDA LinkGeneric 01/2017 - 08/2003
3	Pharmaceutical PreparationsIBA 08/2014 - 09/2009
3	PPAR gammaIBA 01/2009 - 09/2006
3	ThiazolidinedionesIBA 05/2007 - 07/2004
2	FatsIBA 01/2022 - 09/2002
2	Glucagon (Glukagon)FDA Link 09/2021 - 01/2021
2	Indicators and Reagents (Reagents)IBA 01/2021 - 10/2018
2	Dietary ProteinsIBA 12/2020 - 01/2012
2	fibroblast growth factor 21IBA 01/2020 - 11/2016
2	MyokinesIBA 01/2020 - 03/2016
2	Amino Acids FDA Link 01/2018 - 08/2003
2	omega-Chloroacetophenone (Mace)IBA 01/2018 - 03/2016
2	Adenosine Triphosphate (ATP)IBA 04/2017 - 12/2016
2	Naltrexone (ReVia)FDA LinkGeneric 03/2016 - 04/2011
2	Interleukin-6 (Interleukin 6)IBA 03/2016 - 06/2008
2	AdipokinesIBA 01/2016 - 02/2015
2	Growth Hormone (Somatotropin)IBA 02/2015 - 11/2007
2	CeramidesIBA 02/2014 - 09/2009
2	DiglyceridesIBA 06/2011 - 09/2009
2	Anti-Obesity Agents (Antiobesity Drugs)IBA 06/2011 - 06/2011
2	Lipase (Acid Lipase)FDA Link 06/2011 - 09/2009
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2010 - 03/2009
2	Oxygen (Dioxygen)IBA 08/2010 - 03/2009
2	Islet Amyloid PolypeptideIBA 09/2009 - 08/2007
2	pramlintide (Symlin)FDA Link 09/2009 - 08/2007
2	deoxypyridinolineIBA 12/2008 - 04/2003
2	Triiodothyronine (Liothyronine)FDA LinkGeneric 12/2008 - 03/2004
2	Angiotensin Receptor AntagonistsIBA 10/2008 - 12/2004
2	Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA 10/2008 - 12/2004
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2008 - 09/2006
2	Alkaline PhosphataseIBA 06/2008 - 04/2003
2	PPAR alphaIBA 01/2008 - 01/2006
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 09/2006 - 01/2006
2	CholesterolIBA 06/2006 - 01/2006
2	Trans Fatty AcidsIBA 12/2005 - 09/2002
2	Dextroamphetamine (Dexedrine)FDA LinkGeneric 08/2003 - 08/2003
2	Tyrosine (L-Tyrosine)FDA Link 08/2003 - 08/2003
1	AntigensIBA 09/2022
1	AntiemeticsIBA 09/2022

Therapy/Procedure

11	Caloric Restriction 01/2021 - 04/2006
10	Therapeutics 06/2021 - 01/2005
7	Glycemic Control 11/2019 - 01/2011
4	Reducing Diet 01/2022 - 08/2011
4	Fat-Restricted Diet (Diet, Fat Restricted) 06/2019 - 08/2011
3	Protein-Restricted Diet (Diet, Protein Restricted) 12/2020 - 01/2012
3	High-Protein Diet 12/2020 - 01/2012
3	Bariatric Surgery 11/2015 - 06/2011
2	Ketogenic Diet 01/2019 - 08/2016
2	Electrodes (Electrode) 08/2010 - 03/2009
2	Drug Therapy (Chemotherapy) 09/2009 - 12/2004
2	Bed Rest (Bedrest) 12/2008 - 03/2004